Mrs Esther Callcott

Investigating the Therapeutic Properties of Bioactive Compounds Derived from Australian-Grown Coloured Rice.

Obesity, Type II Diabetes and Motor Neuron Disease are all debilitating diseases with limited to no treatments available. The limited treatments that are available have an array of side effects associated with them that can be potentially fatal to the patient. As a result, there is a need to find alternative treatments. Bioactive compounds, in particular phenolic compounds derived from Australian-grown coloured rice, may provide alternative treatments for patients suffering from these diseases. This project aims to identify the potential health benefits of coloured rice using in-vitro and in-vivo biological models.

Prof Chris Blanchard, Dr Abishek Santhakumar,

Australian Research Council Industrial Transformation Centre Scholarship

• Callcott, E.T., Santhakumar, A.B, Luo, J. and Blanchard C.L (2018) Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation. Journal of Applied Biomedicine. Persistent link using digital object identifier

• Callcott, E.T., Rao, S., Santhakumar, A.B, Chinkwo, K.A, Vanniasinkam, T., Luo, J. and Blanchard C.L (2018) Profiling polyphenol composition and antioxidant activity in Australian-grown rice using UHPLC Online-ABTS System. Journal of Cereal Science 80, 174 – 179.

• Callcott, E.T., Santhakumar, A.B, Strappe, P., Luo, J. and Blanchard C.L (2018) Polyphenols from Australian-grown pigmented red and purple rice inhibit adipocyte differentiation. Journal of Cereal Science 81, 140 – 146.
• Callcott, E.T.,Thompson, K., Santhakumar, A.B., Oli, P. and Blanchard C.L (2018) Coloured Rice-derived Polyphenols Reduce Lipid Peroxidation and Pro-Inflammatory Cytokines Ex-Vivo. Food and Function. DOI: 10.1039/C8FO01531G